Endocrine Abstracts

Background: Obesity is one of the most critical problems nowadays, its frequency and consequences. Since the risk of morbidity and mortality increases in obese individuals, lifestyle changes, pharmacotherapy, and bariatric surgery (BS) methods are used for treatment. BS is generally considered the most effective method to treat morbid obesity. However, it is known that thyroid function has a role in weight regulation, the effect of preoperative thyroid function on weight loss ...

Background: Hypoparathyroidism (HypoPT) is a rare condition that is characterized by hypocalcemia and hyperphosphatemia due to low or inappropriately normal serum levels of parathyroid hormone (PTH) for at least 6 months. The long-term complications of hypoparathyroidism indicate the necessity of screening them. In the follow-up of these patients according to hypoparathyroidism guidelines is recommended; calcium, phosphorus, albumin, magnesium, creatinine, and eGFR levels shou...

Background: Primary Hyperparathyroidism (PHPT) is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone. Most often, the presentation of PHPT is asymptomatic. PHPT can manifest with osteoporosis and hypercalciuria as well as with vertebral fractures and nephrolithiasis, both of which can be asymptomatic. Our aim in this study; to determine the frequency of kidney stones in patients operate...

Aim: Contradictory results in limited number of studies were reported about the effects of Ramadan fasting on thyroid hormones. We aimed to evaluate the thyroid functions in Ramadan, and compare late evening or pre-sahour use of levothyroxine in patients being treated for hypothyroidism.Methods: Patients taking levothyroxine for hypothyroidism who were seen in the last one week before Ramadan (8–15 May 2018) and had normal thyroid functions were rec...

Aim: Radioactive iodine (RAI) is one of the treatment approaches in Graves and toxic nodular or multinodular goiter (TNG/TMNG) with low cost and high efficacy. In this study, we aimed to evaluate ultrasonographical and cytological features of thyroid nodules in patients who were treated with radioactive iodine for hyperthyroidism years ago.Methods: Patients who had a history of RAI treatment for hyperthyroidism and had thyroid nodules that were evaluated...

Introduction: Although, familial medullary thyroid cancer is a known condition, familial papillary thyroid cancer (PTC) is a rare and less well described clinical entity. While some studies suggest more aggressive features in familial PTC, some do not support these findings. We aimed to compare ultrasonographical, cytopathological and histopathological results of patients with familial and sporadic PTC.Methods: Data of 194 patients diagnosed with PTC his...

Introduction: Ectopic adrenocorticotrophic hormone (ACTH) syndrome is associated with variable tumor groups most commonly originating from neuroendocrine cells. Here, we reported a patient considered to have nonconvulsive status epilepticus initially due to neurological symptoms and diagnosed as neuroendocrine tumor with ectopic ACTH syndrome.Case: A 85 years old woman with regulated hypertension admitted with partial loss of conciousness. She had cachec...

Introduction: Hepatic dysfunction in hyperthyroidism may occur due to high thyroid hormones, medications or associated autoimmune liver disease. Autoimmune hepatitis or primary biliary cirrhosis (PBC) has rarely been reported in Graves’ disease. We report a patient presenting with pruritus and diagnosed as accompanying PBC and Graves’ disease.Case: A 50 years old female patient applied with progressive pruritus for at least 4 months. Laboratory...

Background: We aimed to evaluate malignancy rate in thyroid nodules ≥4 cm and determine false negativity of fine needle aspiration biopsy (FNAB) in these nodules.Methods: Patients who underwent thyroidectomy between January 2007 and December 2014 in our institution were reviewed. Demographical and clinical data and preoperative ultrasonography (US) findings were obtained from the medical records. The nodules in these patients were grouped as &#8805...

Background: Fine needle aspiration biopsy (FNAB) has proven to be the most valuable diagnostic procedure for preoperative discrimination of benign and malignant nodules. Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has standardized reporting and cytomorphological criteria in aspiration smears. In this study, we aimed to determine malignancy rates in nodules with different cytology results and diagnostic value of TBSRTC for variants of papillary thyroid carcinom...